Single administration of polysaccharide could not induce PRP antibody at a high level in the sera of mice, however, PRP and TT antibodies at high levels were induced in the mice injected with conjugate, and immunological memory was observed. 单独用多糖免疫小鼠未能诱导高水平的血清PRP抗体,而用结合物免疫小鼠却诱导出高水平的血清PRP抗体及TT抗体,并存在免疫记忆性。